Life as nonequilibrium self-organized matter processing information

// PI: Massimiliano Esposito //

The most complex behaviors known in the universe take place in living systems and thanks to unprecedented progress in nano- and bio-technologies we can study them quantitatively down to the molecular level. However, beside evolutionary theory, general principles to guide the quantitative study of living systems are completely missing. 

From our standpoint, living systems are nonequilibrium self-organized forms of matter which extract energy from their surrounding and perform complex information processing and computation tasks to continue to do so in the future. We would like to understand how these behaviors can be understood from existing or possibly new laws of physics. 

At our current toolbox predominantly comprises Thermodynamics and Statistical Physics, Information Theory, Complex Systems Theories.

Most of our present and past focus has been to formulate a theory describing how open chemical reaction networks can process energy an information. While primarily applying to cellular metabolism, many of the concepts and tools we developed also apply to other cellular processes. Connections to other local activities:

  • Skupin: critical transitions in the transcriptome, modelling mitochondria, 
  • Tkatchenko: intra- and inter-molecular free energies, kinetic constants
  • Linster: metabolic repair mechanisms and their thermodynamic cost     

Connections to other international activities: Thermodynamics of Computation: 
https://centre.santafe.edu/thermocomp/Santa_Fe_Institute_Collaboration_Platform:Thermodynamics_of_Computation_Wiki

151 responses to “Life as nonequilibrium self-organized matter processing information

  1. Reading your article helped me a lot and I agree with you. But I still have some doubts, can you clarify for me? I’ll keep an eye out for your answers.

  2. Nice blog here! Also your site loads up very fast! What host are you using? Can I get your affiliate link to your host? I wish my site loaded up as quickly as yours lol

  3. I loved as much as you’ll receive carried out right here. The sketch is tasteful, your authored material stylish. nonetheless, you command get bought an nervousness over that you wish be delivering the following. unwell unquestionably come more formerly again since exactly the same nearly a lot often inside case you shield this hike.

  4. What i don’t understood is in reality how you’re now not really a lot more smartly-favored than you might be now. You’re very intelligent. You understand therefore significantly in terms of this topic, produced me personally believe it from a lot of numerous angles. Its like women and men are not interested except it is one thing to accomplish with Woman gaga! Your own stuffs outstanding. Always care for it up!

  5. Apoiar ferramentas de apostas e estar equipado com uma plataforma diversificada de transações financeiras, a 20Bet oferece suporte tangível aos jogadores. Este é um lugar onde eles podem apostar com dinheiro real, respaldados por concorrentes de diversas disciplinas esportivas. 20bet

  6. I am currently writing a paper that is very related to your content. I read your article and I have some questions. I would like to ask you. Can you answer me? I’ll keep an eye out for your reply. 20bet

  7. I am currently writing a paper that is very related to your content. I read your article and I have some questions. I would like to ask you. Can you answer me? I’ll keep an eye out for your reply. 20bet

  8. I am currently writing a paper that is very related to your content. I read your article and I have some questions. I would like to ask you. Can you answer me? I’ll keep an eye out for your reply. 20bet

  9. I am currently writing a paper that is very related to your content. I read your article and I have some questions. I would like to ask you. Can you answer me? I’ll keep an eye out for your reply. 20bet

  10. Hi my loved one! I wish to say that this post is amazing, nice written and include approximately all vital infos. I’d like to peer more posts like this.

  11. I’ve perused a number of exceptional articles on this site. It’s definitely worth saving for future visits. I’m curious about the tremendous effort you’ve invested in crafting such an informative and outstanding website. I’ll certainly be returning. By the way I am a Senior Researcher @ (Clickmen™)

  12. Excellent blog here! Also your website loads up very fast! What web host are you using? Can I get your affiliate link to your host? I wish my web site loaded up as quickly as yours lol

  13. Simply wish to say your article is as amazing. The clearness in your post is just nice and i could assume you’re an expert on this subject. Well with your permission let me to grab your feed to keep updated with forthcoming post. Thanks a million and please carry on the gratifying work.

  14. I do agree with all the ideas you have introduced on your post. They are very convincing and will definitely work. Still, the posts are very short for newbies. May just you please prolong them a little from subsequent time? Thank you for the post.

  15. I loved as much as youll receive carried out right here The sketch is tasteful your authored material stylish nonetheless you command get bought an nervousness over that you wish be delivering the following unwell unquestionably come more formerly again since exactly the same nearly a lot often inside case you shield this hike

  16. you are truly a just right webmaster The site loading speed is incredible It kind of feels that youre doing any distinctive trick In addition The contents are masterwork you have done a great activity in this matter

  17. Its like you read my mind You appear to know so much about this like you wrote the book in it or something I think that you can do with a few pics to drive the message home a little bit but instead of that this is excellent blog A fantastic read Ill certainly be back

  18. you are in reality a good webmaster The website loading velocity is amazing It sort of feels that youre doing any distinctive trick Also The contents are masterwork you have done a fantastic job in this topic

  19. I agree with all of the thoughts you have presented in your article; they are incredibly persuasive and will indeed be effective. However, the postings are extremely brief for beginners; could you perhaps make them a little longer in future? Thank you for the post.

  20. Thanks I have recently been looking for info about this subject for a while and yours is the greatest I have discovered so far However what in regards to the bottom line Are you certain in regards to the supply

  21. Simply desire to say your article is as surprising The clearness in your post is simply excellent and i could assume you are an expert on this subject Fine with your permission let me to grab your feed to keep up to date with forthcoming post Thanks a million and please carry on the gratifying work

  22. Instagram’da takipçi, beğeni ve izlenme gibi hizmetleri sunan takiple.com.tr, kullanıcıların hesaplarını daha etkili bir şekilde yönetmelerine ve platformdaki etkileşimlerini artırmalarına yardımcı olabilir.

  23. Ce que je ne réalise pas, c’est que vous n’êtes pas beaucoup plus favorisé que vous ne l’êtes actuellement. Vous êtes très intelligent. Vous reconnaissez considérablement ce sujet, ce qui m’a permis de le voir sous de nombreux angles. Les hommes et les femmes ne sont pas fascinés par Lady Gaga.

  24. Wow, wonderful blog layout! How long have you been blogging for? you make blogging look easy. The overall look of your site is great, as well as the content!

  25. Here, I’ve read some really great content. It’s definitely worth bookmarking for future visits. I’m curious about the amount of work you put into creating such a top-notch educational website.

  26. Merci J’ai cherché des informations sur ce sujet pendant un certain temps et vous êtes le meilleur que j’ai trouvé jusqu’à présent Cependant, qu’en est-il de la ligne de fond ?

  27. My brother suggested I might like this blog He was totally right This post actually made my day You can not imagine simply how much time I had spent for this info Thanks

  28. upysm.com 是一個專業的社交媒體推廣平台,提供各種刷粉絲服務,讓您的Instagram、Facebook、Youtube等帳號快速增加人氣和影響力。無論您是個人創作者還是企業品牌,我們都可以為您量身定制最合適的方案,讓您在社交媒體上脫穎而出。

  29. Wow, superb blog layout! How long have you been blogging for? you make blogging look easy. The overall look of your site is magnificent, as well as the content!

  30. I loved as much as you will receive carried out right here. The sketch is attractive, your authored material stylish. nonetheless, you command get got an impatience over that you wish be delivering the following. unwell unquestionably come more formerly again since exactly the same nearly a lot often inside case you shield this hike.

  31. Elevate your website’s quality with Toolifygo! Our suite of SEO, text, and image tools is designed to enhance every aspect of your online presence. Make your site irresistible to both search engines and audiences. Experience the uplift with Toolifygo today.

  32. This webpage is phenomenal. The brilliant data reveals the proprietor’s interest. I’m awestruck and expect further such astonishing entries.

  33. ✔️꽁타✔️ggongta.com,꽁머니 커뮤니티,꽁머니이벤트 [농구] 3월13일 19:00 WKBL 하나원큐 vs KB스타즈 +0

  34. you are truly a just right webmaster. The site loading speed is incredible. It kind of feels that you’re doing any distinctive trick. In addition, The contents are masterwork. you have done a great activity in this matter!

  35. Thank you for your sharing. I am worried that I lack creative ideas. It is your article that makes me full of hope. Thank you. But, I have a question, can you help me?

  36. Hi my family member I want to say that this post is awesome nice written and come with approximately all significant infos I would like to peer extra posts like this

  37. Your writing has a way of resonating with me on a deep level. It’s clear that you put a lot of thought and effort into each piece, and it certainly doesn’t go unnoticed.

  38. German: “Super Artikel! Die Informationen waren wirklich hilfreich und interessant. Es ist immer toll, so gut recherchierte Inhalte zu finden. Weiter so! Ich bin gespannt darauf, in Zukunft mehr von dir zu lesen.”English: “Excellent article! The information was truly helpful and interesting. It’s always great to find such well-researched content. Keep it up! I look forward to reading more from you in the future.”

  39. The point of view of your article has taught me a lot, and I already know how to improve the paper on gate.oi, thank you.

  40. Привет всем!

    Всем привет, друзья-казиношники! Сегодня я расскажу вам о своих любимых онлайн-казино и поделюсь личным опытом игры на реальные деньги. Поверьте, я перепробовал столько сайтов и приложений, что могу смело называть себя экспертом в этой области! Кстати, об играх! Я обожаю слоты с прогрессивными джекпотами – это же настоящий адреналин! Но если хотите почувствовать себя VIP-персоной, попробуйте игры с живыми дилерами. Атмосфера реального казино, профессиональные крупье и возможность пообщаться с другими игроками – что может быть круче
    И напоследок мой главный совет: не забывайте про мобильные приложения казино! Со смартфоном удача всегда будет у вас в кармане, и вы сможете сорвать куш в любом месте и в любое время. Просто скачайте приложение на андроид или айфон, пройдите быструю регистрацию – и вперед, покорять азартные вершины!
    Ну что, друзья, готовы к новым свершениям и большим выигрышам Тогда вперед, в мир онлайн-казино! И пусть фортуна всегда будет на вашей стороне!
    pig-landtin.mn.co

    скачать официальный сайт казино
    мобильное приложение казино ru cool air org
    игровые автоматы на реальные деньги для андроид скачать
    казино на деньги приложение для телефона
    oy casino официальный сайт

    Удачи!

  41. Привет всем!
    Для максимального удобства я настоятельно рекомендую скачать приложение казино на ваш Android. Это позволит вам играть в любимые игры в буквальном смысле на ходу, где бы вы ни находились. Некоторые казино даже предлагают бездепозитные бонусы, чтобы вы могли опробовать игры без риска потери собственных средств. Обратите внимание на лицензированные казино с приложениями для Android. Они гарантируют честную игру, безопасность ваших данных и денежных операций. Кроме того, качественные приложения обеспечивают плавную и стабильную работу без задержек и сбоев.
    https://flerus-shop.hcp.dilhost.ru/club/user/3/forum/message/630/626/

    скачать казино на андроид на реальные деньги
    виртуальное казино бездепозитный бонус
    казино android
    бонусы казино
    казино миллион промокоды

    Удачи!

  42. Доброго!

    Друзья, я не могу в своем блоге рекомендовать азартные игры и онлайн-казино или делиться советами, как в них играть. Это было бы безответственно с моей стороны, ведь игромания – серьезная проблема, разрушающая жизни.
    Поверьте, я и сам когда-то увлекался онлайн-слотами, мечтая легко разбогатеть. Яркие обещания казино затягивали как омут. Но в итоге я лишь влез в долги и чуть не потерял семью. Хорошо, что вовремя одумался.
    Сейчас я четко понимаю – все эти заманчивые рекламные посылы о быстрых выигрышах и постоянной удаче созданы лишь для того, чтобы опустошить наши карманы. Математика и алгоритмы казино всегда работают против игрока. Единственный, кто там стабильно зарабатывает – сами казино.
    Поэтому мой совет – держитесь подальше от азартных игр онлайн. Это путь к разочарованию и проблемам, а не к успеху. Лучше инвестируйте время и деньги в себя, близких, в реальное дело. Стройте жизнь на позитиве, а не на иллюзорной надежде сорвать куш.
    Не позволяйте индустрии азартных игр манипулировать вами. Цените то, что имеете, и помните – настоящее богатство в любви, здоровье, увлеченности любимым делом, а не в погоне за случайной удачей. Будьте мудрыми и не попадайтесь на крючок!
    info-pro.kz

    казино официальный мобильная версия
    казино где можно использовать мир на андроид
    игровые автоматы на реальные деньги для андроид скачать
    казино на деньги casino официальный мобильная
    онлайн казино на деньги андроид

    Удачи!

  43. This article was incredibly insightful! I was captivated by the thoroughness of the information and the clear, engaging way it was delivered. The depth of research and expertise evident in this post is remarkable, significantly elevating the content’s quality. The insights in the opening and concluding sections were particularly compelling, sparking some ideas and questions I hope you will explore in future articles. If there are any additional resources for further exploration on this topic, I would love to delve into them. Thank you for sharing your expertise and enriching our understanding of this subject. I felt compelled to comment immediately after reading due to the exceptional quality of this piece. Keep up the fantastic work—I’ll definitely be returning for more updates. Your dedication to crafting such an excellent article is highly appreciated!

  44. This article was incredibly insightful! I was captivated by the thoroughness of the information and the clear, engaging way it was delivered. The depth of research and expertise evident in this post is remarkable, significantly elevating the content’s quality. The insights in the opening and concluding sections were particularly compelling, sparking some ideas and questions I hope you will explore in future articles. If there are any additional resources for further exploration on this topic, I would love to delve into them. Thank you for sharing your expertise and enriching our understanding of this subject. I felt compelled to comment immediately after reading due to the exceptional quality of this piece. Keep up the fantastic work—I’ll definitely be returning for more updates. Your dedication to crafting such an excellent article is highly appreciated!

  45. Your work was remarkably enlightening! The thoroughness of the information and the riveting delivery enthralled me. The depth of research and proficiency evident throughout significantly heightens the content’s excellence. The insights in the introductory and concluding portions were particularly compelling, sparking new concepts and inquiries that I hope you’ll explore in future writings. If there are additional resources for further delving into this topic, I’d be eager to immerse myself in them. Gratitude for sharing your expertise and enriching our understanding of this subject. The exceptional quality of this piece compelled me to comment promptly after perusing. Continue the fantastic work—I’ll certainly return for more updates. Your dedication to crafting such an outstanding article is highly valued!

  46. Your piece was tremendously insightful! The comprehensiveness of the material and the engaging presentation captivated me. The extent of research and expertise apparent throughout substantially elevates the content’s caliber. The revelations in the opening and closing sections were particularly compelling, igniting novel ideas and queries that I hope you’ll investigate in future works. If there are supplementary resources for further exploration on this subject, I’d be delighted to immerse myself in them. Thank you for sharing your knowledge and enriching our grasp of this topic. The exceptional quality of this work prompted me to comment right after reading. Maintain the fantastic efforts—I’ll definitely revisit for more updates. Your commitment to crafting such an excellent article is greatly appreciated!

Leave a Reply

Your email address will not be published. Required fields are marked *